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Cannabis-like compound prevents bone loss
UPI.com, 5th January 2006| Israeli researchers have developed a prototype drug to prevent osteoporosis using substances produced in the body that act like those found in cannabis. Researchers from the Bone Laboratory of the Hebrew University found that endocannabinoids, which are produced mainly in the brain, are present also in the bone and other tissues and have similar effects to those of the active components in hashish and marijuana, produced from the cannabis plant. The study, published in the journal PNAS (Proceedings of the National Academy of Sciences of the U.S.A.), says endocannabinoids bind to and activate two receptors, CB1 and CB2. A study of genetically engineered mice lacking the CB2 receptor found that the CB2-deprived mice developed severe osteoporosis, similar to that which appears in humans. The researchers have developed a new synthetic compound, HU-308, which activates CB2 and slows the development of osteoporosis in mice. This compound forms the basis for a cannabinoid-based, anti-osteoporotic type drug which has also been found to be free of any psychoactive side effects. |
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Comments
To eat more calcium rich and enriched foods.
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Add Your Comment
Hi,
Are Safe for Someone With Severe Osteoporosis It is important that you continue to exercise for the recommended amount of 30 minutes per day or more and that you include some moderate-intensity exercise in your routine. The key is to make sure you don’t overexert yourself while working out. If you feel any pain or strain with exercise, then you need to reevaluate and redirect the kinds of things you’re doing. Talk with your doctor about a change in your exercise program.
Thanks..
Prevent Osteoporosis
Posted by on 10th Oct 09 at 5:44 am